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Each Journal Watch Online CME exam contains 4 questions. Each question is drawn from a single original article summary: To review the full text of the relevant summary for each question, please click on the "view summary" hyperlink that follows the question. All questions must be answered correctly before CME credit is issued, but you'll have unlimited chances to answer the questions correctly. Choose the best answer for each question before clicking "SUBMIT." The correct answers are highlighted in this sample exam.

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Category: Women's Health

JW (General): Hormone therapy, Obesity, Tamoxifen, Birth size

QUESTION 1

Investigators have analyzed data from the Women's Health Initiative to determine whether women who receive continuous estrogen/progestin (E/P) therapy experience an improvement in quality of life. Based on the findings, which statement is false?
View summary

  A.

At 1 year, users of E/P experienced significant benefit in terms of less sleep disturbance, better physical functioning, and less pain.

  B.

At 1 year, younger women who used E/P reported benefit only for vasomotor symptoms and sleep disturbances.

  C. Findings from this study support the long-term use of E/P in asymptomatic postmenopausal women.
  D. Younger symptomatic women might benefit from short-term E/P therapy to ease their transition through menopause.


QUESTION 2
In a prospective study, researchers followed about 900,000 Americans for 16 years and collected information on cancer mortality. Height and weight information were recorded at baseline. All of the following statements are true EXCEPT:
View summary

  A.

Higher baseline body-mass index was associated with higher risk for cancer mortality.

  B.

Higher death rates from cancer were not associated with marked obesity.

  C. Weight loss protected against cancer mortality.
  D. The analysis accounted for many potential confounders, such as smoking and diet.


QUESTION 3
In a North American study, researchers evaluated 3 treatment regimens for preventing ipsilateral recurrence of breast cancer after lumpectomy of lesions measuring 1 cm or smaller. Which treatment regimen was most effective?
View summary

  A.

Radiation plus tamoxifen

  B.

Radiation plus placebo

  C. All 3 regimens were equally effective
  D. Tamoxifen alone


QUESTION 4
In a retrospective study, Swedish investigators evaluated the association between birth size and premenopausal breast cancer among more than 5000 Swedish women. Which statement is true?
View summary

  A.

Rates of breast cancer were 5 times higher in women whose birth lengths and head circumferences were in the highest quintile.

  B.

Larger size for gestational age was not associated with increased risk for premenopausal breast cancer.

  C. A large proportion of breast cancers in a given population can be attributed to birth size.
  D. Size at birth was associated positively with rate of breast cancer in premenopausal women.

 

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